RAF Typhoon jets have operated alongside French warplanes in a combined operation targeting an subterranean weapons facility in Syria used by the IS group, per a report from the UK's MoD.
The site, pinpointed through surveillance, was assessed as containing munitions and bombs, the release indicated, and was positioned in mountainous terrain just north of the historic site of Palmyra in central Syria.
"The RAF jets utilized Paveway IV guided bombs to hit a number of entry passages leading to the depot... preliminary assessments suggest the objective was successfully hit," officials stated.
There was no sign of any civilian casualties in the operation on Saturday evening and all the aircraft returned safely, the ministry further stated.
The British jets were supported by a Voyager aerial refuelling aircraft.
The Islamic State group - also known as Daesh - established jihadist rule over parts of Syria and Iraq before its territorial defeat in 2019.
"This operation shows the UK's leading role, and determination to operate in unison with allied nations, to eradicate any re-emergence of Daesh and their dangerous and violent ideologies in the region," UK Defence Secretary the minister said.
UK warplanes have performed surveillance missions over Syrian airspace to "forestall any efforts to regroup" of IS subsequent to its routing at the Baghuz confrontation in the year 2019, the ministry said.
"I must thank all the members of British forces participating in this mission for their professionalism and their courage," he added. "They were among thousands of British personnel on duty over Christmas and New Year. This mission, to take out dangerous terrorists who endanger our way of life, shows how our armed forces are prepared to act, throughout the year, keeping Britain secure within its borders and influential overseas."
Last December, the United States armed forces carried out what it described as a "massive strike" against Islamic State objectives in Syria, after an assault killed two US troops and a civilian interpreter in the Palmyra area.
The U.N. says IS still has between 5,000 and 7,000 combatants in Iraq and Syria.